A. M. Rostami
Nicholas Maiale Distinguished professor of Neurology Chairman, Department of Neurology Thomas Jefferson University
A.M. Rostami, MD, PhD, is the Nicholas Maiale Distinguished Professor and Chair of Neurology at Thomas Jefferson University.
He leads the Multiple Sclerosis and Neuroimmunology Research Laboratory, focusing on immune mechanisms of inflammatory demyelinating diseases including multiple sclerosis.
His work spans molecular neuroimmunology, myelin repair, and emerging vesicle based therapies for autoimmune diseases.
He is internationally recognized for advancing translational research in MS and other neuroimmune disorders.
Seminars
Thursday 24th September 2026
Exosomes Derived from Oligodendrocytes for Therapy of CNS Autoimmune Inflammatory Diseases
1:30 pm
- Current therapies for CNS autoimmune diseases are generalized immunosuppressant. There is a clear need for antigen-specific therapies that remove auto-reactive immune cells and leave the rest of immune system intact
- Induction of antigen-specific immunological tolerance can help suppress the autoreactive immune cells without systemic immunosuppression
- Exosomes from the target cells in autoimmune diseases can be used to induce immune tolerance to only target cell antigens, and examples of this novel therapeutic approach will be presented
