Christopher Paradise
Senior Vice President, Research & Development RION Health Inc.
Chris Paradise serves as SVP of Research and Development at Rion, Inc. He holds a PhD in Molecular Pharmacology and Regenerative Medicine from the Mayo Clinic in Rochester, MN. Before joining Rion, Chris’s research efforts focused on engineering adult stem cells to create novel therapeutics for tissue regeneration. At Rion, Chris has been involved in the translation of Rion’s platelet-derived exosome therapeutic from its origins within the academia laboratories at the Mayo clinic to a clinical-stage Drug Product under evaluation in late-stage human clinical trials.
Seminars
- Establishing potency assays that reflect the proposed mechanism of action, including immunomodulation, angiogenesis or tissue repair
- Moving beyond surrogate markers to functional readouts that capture biologically relevant exosome activity
- Correlating in vitro potency with in vivo efficacy to support clinical translation and dose justification
- Honing Rion’s platelet-derived exosome technology and application in regenerative medicine
- Reviewing outcomes from ongoing clinical programs in advanced wound care and musculoskeletal diseases
- Presenting additional, future applications of exosome-based technologies as a therapeutic platform