Pranav Sharma
Founder & Chief Executive Officer Xosomix Therapeutics
Dr. Pranav Sharma is the founder and CEO of Xosomix, a biotechnology company developing exosome-based therapeutics and diagnostics for neurological disorders and women’s health. He is a neuroscientist, cell biologist, and biophysicist whose research has focused on exosome-mediated cellular communication and neurodevelopmental disorders such as Rett syndrome. Sharma earned his Ph.D. in biophysics and cell biology from the National Centre for Biological Sciences in India and completed postdoctoral research at Cold Spring Harbor Laboratory and Scripps Research. His scientific work includes discoveries in neural stem cell biology, lipid raft structure, and cellular endocytosis, helping advance next-generation drug delivery technologies.
Seminars
- Managing biological variability in exosome preparations through well-defined reference standards and controls
- Implementing cell-based and functional assays with high sensitivity and reproducibility across manufacturing batches
- Establishing assay validation frameworks to ensure robustness, precision, and regulatory compliance
- Selecting fit-for-purpose animal models that reflect disease relevance, biodistribution, and immunological response to exosome-based interventions
- Establishing translational pharmacology frameworks linking dose, exposure, and functional response across in vitro and in vivo systems
- Integrating safety pharmacology, toxicology, and biodistribution studies to de-risk first in-human clinical trial design
