Exosomes Derived from Oligodendrocytes for Therapy of CNS Autoimmune Inflammatory Diseases

• Current therapies for CNS autoimmune diseases are generalized immunosuppressant. There is a clear need for antigen-specific therapies that remove auto-reactive immune cells and leave the rest of immune system intact
• Induction of antigen-specific immunological tolerance can help suppress the autoreactive immune cells without systemic immunosuppression
• Exosomes from the target cells in autoimmune diseases can be used to induce immune tolerance to only target cell antigens, and examples of this novel therapeutic approach will be presented

Speakers:

A. M. Rostami

Nicholas Maiale Distinguished professor of Neurology Chairman, Department of Neurology

Thomas Jefferson University