Exosomes Derived from Oligodendrocytes for Therapy of CNS Autoimmune Inflammatory Diseases
- Current therapies for CNS autoimmune diseases are generalized immunosuppressant. There is a clear need for antigen-specific therapies that remove auto-reactive immune cells and leave the rest of immune system intact
- Induction of antigen-specific immunological tolerance can help suppress the autoreactive immune cells without systemic immunosuppression
- Exosomes from the target cells in autoimmune diseases can be used to induce immune tolerance to only target cell antigens, and examples of this novel therapeutic approach will be presented